以月桂酸为原料,与N,N-二甲基-1,3-丙二胺在氢氧化钾为催化剂的碱性条件下缩合反应生成月桂酸酰胺丙基二甲基胺(PKO12),再与3-氯-2-羟基丙磺酸钠进行季铵化反应合成月桂酰胺丙基-2-羟基-3-磺基甜菜碱(LHSB)。通过讨论反应方式及反应条件(时间、温度、用量)等对转化率的影响,得出了缩合反应和季铵化反应的优化合成工艺条件。最终产物LHSB的临界胶束浓度(CMC)为1 mmol/L、CMC下的表面张力为18.16 mN/m、起泡高度为10.5 cm、稳泡性能达到0.90,具有广泛的应用前景。

Lauric acid amidopropyldimethylamine (PKO12) is synthesized through a condensation reaction between lauric acid and N,N-dimethyl-1,3-propanediamine in the presence of KOH under alkaline conditions.Laurylamide propyl-2-hydroxy-3-sulfobetaine (LHSB) is obtained through a quaternization reaction between PKO12 and 3-chloro-2-hydroxypropanesulfonic acid sodium salt.The optimal synthesis conditions for LHSB are investigated through a single-factor experiment,and the product samples are characterized by means of infrared spectroscopy.It is found that LHSB has a critical micelle concentration (CMC) of 1×10^-3 mol·L^-1,a surface tension at CMC of 18.16 mN·m^-1,a foaming height of 10.5 cm,and a foam stability of 0.90,showing a promising application prospect.

李柳月(1997-),女,硕士生,研究方向为生物基表面活性剂,672441994@qq.com。