基于恒收率的时间优化模型，利用膜洗滤过程中在线反馈的数据，创新性地提出"走一步看一步"的优化策略，拓展得到了洗滤过程的即时优化模型。结果表明，采用该模型能够解决膜洗滤过程顶洗起点的在线判断问题，避免了为获取相应参数值进行的离线测试实验，能够为工业生产膜洗滤过程的在线优化与控制提供关键理论支撑。

Based on the time optimization model of constant yield and by using the online feedback data in membrane diafiltration process,the "step by step" optimization strategy is innovatively constructed and expanded into the real-time optimization model for membrane diafiltration process.The results show that the model can solve the problem in judging on-line the starting point of dilution step of diafiltration process.Based on the model,it can avoid the off-line test experiment to obtain the corresponding parameter values,and provide important theoretical support for on-line optimization and control of membrane diafiltration process oriented to industrial production.

陈丽红(1995-),女,硕士生,研究方向为膜分离技术,18000107@smail.cczu.edu.cn