研究了氯化胆碱-乙酸组成的低共熔溶剂在提取槲树叶中黄酮类物质的应用。考察了氯化胆碱-乙酸体系的摩尔比、含水质量分数、提取温度、提取时间、液固比对黄酮类物质芦丁提取量的影响；在单因素的基础上进行了响应面分析。得到最佳的实验条件：n（氯化胆碱）：n（乙酸）=1：3、含水质量分数为30%、提取温度为61℃、液固比为51 mL/g、提取时间为85 min，此时，芦丁平均提取量为58.79 mg/g。

The application of choline chloride-acetic acid eutectic solvent in the extraction of flavonoids from quercus leaves is studied.The effects of the composition ratio of choline chloride-acetic acid system, water content, extraction temperature, extraction time and liquid-solid ratio on the extraction amount of rutin are evaluated.Response surface analysis is carried out on the basis of single factor.The optimum conditions are determined as follows:the molar ratio of choline chloride to acetic acid is 1:3, water content is 30%(W/W), extraction temperature is at 61℃, the liquid-solid ratio is 51 mL·g^-1, and extraction lasts for 85 min.Under the optimal conditions, the average extraction amount of rutin reaches 58.79 mg·g^-1.

沈豪玲(1995-),女,硕士研究生,研究方向为生物质研究,shl18595836034@163.com