考察自制聚苯乙烯基球形活性炭（PACS_S）对尿毒症毒素DL-β-氨基异丁酸（DL-β-AIBA）的吸附性能，以探究其治疗慢性肾病的可能性。测定了4种活性炭对DL-β-AIBA的吸附等温线、吸附动力学曲线及3 h内吸附率。结果表明，DL-β-AIBA在球形活性碳上的吸附行为符合Freundlich吸附等温线，平衡吸附量与比表面积无关，而与孔径范围在0.6~0.8 nm的超微孔容积有较好的线性关系。动力学符合拟二级动力学模型，颗粒内扩散不是唯一的控速步骤。3 h内，4种活性炭对DL-β-AIBA的吸附率可达40%以上（最高52%），是相同条件下商品药用炭的2.3~3倍，表明其在短时间内对DL-β-AIBA具有较强的吸附能力。

The ability of self-prepared polystyrene-based spherical activated carbons (PACS_S) to remove DL-β-aminobutyric acid (DL-β-AIBA),a kind of uremic toxin,is investigated to explore possibility of curing chronic renal disease.The adsorption equilibrium,adsorption kinetic curves and 3 h adsorption rates of 4 kinds of activated carbons for DL-β-AIBA are measured.Results reveal that the adsorption action of DL-β-AIBA on PACS_S fits Freundlich adsorption isotherm well.The equilibrium adsorption amount of DL-β-AIBA is independent on specific surface area,but has a good linear relationship with the micro pore volume of pore diameter between 0.6-0.8 nm.The adsorption kinetics is found to comply with the pseudo-second-order equation,and the internal diffusion is not the only rate-controlling step.Within 3 hours,adsorption rates of four kinds of activated carbons against DL-β-AIBA are all higher than 40% (up to 52%),which is 2.3-3 times that of medical charcoal under the same conditions,illustrating that the spherical activated carbon has a good adsorption capacity for DL-β-AIBA.

包燕君(1990-),女,硕士,研究方向为球形活性炭的制备及应用,15021592619@163.com