Abstract: Fe3O4@PDA-NaIO4 and Fe3O4@PDA are synthesized through functionalizing oil/water soluble magnetic nanoparticles by polydopamine (PDA) under different oxidation conditions.Through a series of characterizations, it is found that both Fe3O4@PDA-NaIO4 and Fe3O4@PDA exhibit good dispersion and carry opposite charges at pH=7.0(+29.9 mV and -26.3 mV), which is due to the different compositional structures of PDA on both surfaces.In addition, the saturation magnetization intensity of these two particles is 48.80 emu·g-1 and 62.11 emu·g-1, respectively, both showing superparamagnetic.In conclusion, the synthesized PDA-functionalized magnetic nanoparticles are expected to be applied in biomedical fields such as nuclear magnetic resonance imaging and targeted drug delivery.
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