Abstract: A novel continuous synthesis process for dimethyldiallylammonium chloride in a microreactor is designed.The influences of reaction temperature,molar ratio of raw materials and residence time on the reaction are observed,and the process is modified from single-factor conditional experiment.It is found that the product yield reaches 92% under the optimized conditions that n(dimethylamine)∶n(sodium hydroxide)∶n(allyl chloride)=1∶1∶2.1,reaction temperature is 45℃ and residence time is 11 min.Compared with traditional one-step process,the microreactor process can simplify procedures,shorten reaction time,and realize higher yield.
李忠于, 黄伟, 管庆宝, 秦涛. 微反应器中合成二甲基二烯丙基氯化铵的研究[J]. 现代化工, 2021, 41(7): 205-207,213.
LI Zhong-yu, HUANG Wei, GUAN Qing-bao, QIN Tao. Research on synthesis of dimethyldiallylammonium chloride in a microreactor. Modern Chemical Industry, 2021, 41(7): 205-207,213.
[1] 朱涛,李潇潇,曾碧涛.季铵盐类阳离子单体的合成工艺研究进展[J].化学研究与应用,2014,26(10):1527-1533. [2] Wandrey C,Hernandez-Barajas J,Hunkeler D.Diallyldimethylammonium chloride and its polymers[J].Adv Polym Sci,1999,145:123-182. [3] 郑亚锋,赵阳,辛峰,等.微反应器研究及展望[J].化工进展,2004,23(5):461-467. [4] 李斌.微反应器技术在精细化工中的应用[J].精细化工,2006,23(1):1-7. [5] Qu W L,Mudawar I.Flow boiling heat transfer in two-phase micro-channel heat sinks:Ⅰ.Experimental investigation and assessment of correlation methods[J].Inter J Heat and Mass Trans,2003,46(15):2755-2771. [6] Li S W,Wu J H,Wang Y,et al.Mesomixing scale controlling and its effect on micromixing performance[J].Chem Eng Sci,2007,62(13):3620-3626. [7] 张跃,李津石,严生虎,等.微通道反应器中二氯丙醇环化反应研究[J].现代化工,2012,32(2):82-86. [8] 刘建武,郭成,严生虎,等.连续流微通道反应器中二氯丙醇合成环氧率丙烷的浓度分布及动力徐分析[J].精细石油化工,2015,32(6):68-71. [9] 胡小明,姚干兵,郝成君.二甲基二烯丙基氯化铵的合成[J].大众科技,2007,(8):122-123. [10] Dummann G,Quittmenn U,Groschel L,et al.The capillary-microreactor:A new reactor concept for the intensification of heat and mass transfer in liquid-liquid reactions[J].Catal.Today,2003,79:433-439. [11] 徐金虎,徐国亮,郑磊.低温两步法合成二甲基二烯丙基氯化铵的研究[J].山西化工,2008,(2):8-10.