Purification of o-iodoaniline by melt crystallization
XU Kui1, ZHU Jing1, HU Xue1, WANG Rui-zhe1, LI Hong-guo1, LI Tian-xiang1,2
1. School of Chemistry and Chemical Engineering, Guizhou University, Guiyang 550025, China; 2. National Key Laboratory for Efficient Utilization of Low Grade Phosphate Rocks and Their Associated Resources, Guiyang 550005, China
Abstract: Crude o-iodoaniline mixtures are separated and purified by melt crystallization.Effects of cooling rate,final temperature in the crystallization process,crystal growing time,heating rate and final temperature in the sweating process on the yield and purity of the product are investigated and analyzed.The results show that 99.07% o-iodoaniline can be obtained with a yield of 61.75% when the initial concentration of o-iodoaniline in crude mixtures is 70.95%,the cooling rate is 0.3 K·min-1,the final crystallization temperature is 301.15 K,crystal growing time is 2 h and the heating rate in sweating process is 0.2 K·min-1 and the final sweating temperature is 313.15 K.
许奎, 朱静, 胡雪, 王睿哲, 李红果, 李天祥. 熔融结晶法提纯邻碘苯胺工艺[J]. 现代化工, 2019, 39(3): 136-138,140.
XU Kui, ZHU Jing, HU Xue, WANG Rui-zhe, LI Hong-guo, LI Tian-xiang. Purification of o-iodoaniline by melt crystallization. Modern Chemical Industry, 2019, 39(3): 136-138,140.
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