在釜式反应器内进行6-羟基己酸甲酯加氢制备1,6-己二醇的工艺研究,考察了反应温度、反应压力、催化剂质量分数和反应时间等因素对催化加氢过程的影响,并采用气相色谱仪分析监测6-羟基己酸甲酯催化加氢制备1,6-己二醇的反应进程,得到最优工艺条件:温度为200 ℃、压力为7 MPa、催化剂质量分数为8 %、反应时间为6 h。进一步采用核磁共振氢谱和红外光谱等分析手段对产品进行结构确认,结果表明,6-羟基己酸甲酯的转化率达99 %,1,6-己二醇选择性最高可达86 %。

The process for preparing 1,6-hexanediol from methyl 6-hydroxyhexanoate is studied in a reactor loaded with copper-based catalyst.The impacts of reaction temperature,reaction pressure,catalyst dosage,and reaction time on the catalytic hydrogenation process are evaluated.Gas chromatography analysis is employed to monitor the reaction process,and the optimal process conditions are obtained as follows:temperature is 200℃,pressure is 7 MPa,catalyst dosage is 8 %,and reaction time is 6 h.Analysis methods such as nuclear magnetic resonance hydrogen spectroscopy and infrared spectroscopy are employed to confirm the structure of the product again.It is found that a new process is obtained with a conversion rate of 99 % for methyl 6-hydroxyhexanoate and a selectivity of 86 % for 1,6-hexanediol.

范丽敏(1999-),女,硕士生,研究方向为化工过程安全,1963917158@qq.com