采用KOH热处理方法对沥青基球形活性炭进行改性，并通过BET、Zeta电位和XPS对活性炭进行表征。利用溶菌酶模拟中分子尿毒症毒素β2-微球蛋白，测定改性前后活性炭对溶菌酶的2 h吸附率，从而推测对β2-微球蛋白的吸附能力。同时，探究了改性条件对活性炭吸附性能的影响。结果表明，2 h内未改性的活性炭吸附率为42.54%，改性活性炭吸附率最高可达76.54%，提高了83.19%。Zeta电位和活性炭中9~80 nm范围内的孔容是影响活性炭对溶菌酶吸附性能的因素，整个吸附过程主要由孔结构和静电作用控制。

Pitch-based spherical activated carbon is modified by potassium hydroxide (KOH) heat treatment,and characterized by BET,Zeta potential and XPS.Taking lysozyme to simulate the middle molecular uremic toxin β2-microglobulin,the 2 h adsorption efficiencies of activated carbon on lysozyme before and after modification are determined,so as to speculate its adsorption capacity to β2-microglobulin.The effects of modification conditions on the adsorption performance of activated carbon are investigated.Results show that within 2h,the adsorption efficiency of the unmodified activated carbon is 42.54% while that of the modified activated carbon is up to 76.54%,an increase of 83.16%.Zeta potential and the pore volume of pores in the 9-80 nm pore size range in activated carbon are the factors affecting its adsorption performance,and the entire adsorption process is mainly controlled by pore structure and electrostatic interaction.

郭怡悦(1997-),女,硕士研究生,研究方向为活性炭在血液灌流中的应用,guojoyy@163.com