提出了基于遗传规划（GP）的更新型精馏-膜分离集成过程综合求解策略，对共沸物系分离进行优化计算；该综合求解策略可以应用于尚处于实验研究阶段的膜计算。以甲醇-甲苯共沸物系和壳聚糖膜为计算实例，研究了混合型膜应用于同一精馏-膜分离集成流程的经济效益等内容。计算结果表明，混合型膜同时应用于同一集成过程可以降低精馏-膜分离集成过程成本，提高膜的应用可行性。GP综合求解策略具备可扩展性和广泛适用性，可以适用于针对任何共沸物系分离快速计算出其最优精馏-膜分离集成流程。

A comprehensive solution strategy based on genetic programming (GP) for integrated distillation-membrane separation process is proposed to optimize the separation of azeotropic system.This strategy can be applied to membrane calculation which is still in experimental research stage.Taking methanol-toluene azeotrope system and chitosan membrane as calculation examples,the economic benefits are studied for applying mixed membrane in the same distillation-membrane separation integration process.Calculation results show that the application of mixed membrane in the same integrated process can reduce the cost of distillation-membrane separation integration process and improve the feasibility of membrane application.This GP comprehensive solution strategy has the expansibility and wide applicability.It can be used to calculate the optimal distillation-membrane separation integration process for any azeotropic system.