采用共混法将壳聚糖（CS）和羟丙基甲基纤维素（HPMC）共混后制备一系列CS/HPMC溶液。考察了CS、HPMC、甘油（Gyl）质量分数以及HPMC分子质量对体系最低临界转变温度（LCST）的影响。同时，探究CS/HPMC/Gyl水凝胶最佳制备质量比为1：5：60。通过SEM、流变仪对该体系进行了表征，讨论了CS/HPMC/Gyl体系凝胶的温敏性、流变性和黏弹性。结果表明，CS/HPMC/Gyl溶液体系具有一定的温敏性，且在反应后的储能模量均大于损耗模量；在CS/HPMC/Gyl溶液体系中，同一低黏度下的HPMC在同一剪切频率下随着HPMC质量分数的增大剪切黏度增大。

Chitosan (CS) and hydroxypropyl methylcellulose (HPMC) are blended together to prepare a series of CS/HPMC solutions.The effects of CS content,HPMC content,glycerol (Gyl) content and HPMC molecular weight on the system's lowest critical transition temperature (LCTT) are studied.It is found that the optimal preparation ratios of CS/HPMC/Gyl hydrogel system is 1:5:60.The system is characterized by SEM and rheometer,and its temperature sensitivity,rheology and viscoelasticity are discussed.Results show that the CS/HPMC/Gyl solution system exhibits a certain temperature sensitivity,and its energy storage modulus after reaction is greater than the loss modulus.In a CS/HPMC/Gyl solution system,at the same shear frequency,the shear viscosity of HPMC increases with the increasing HPMC mass fraction.

王俊(1965-),男,博士,教授,主要从事精细化学品合成及高分子材料的研究,wangjun1965@yeah.net