Based on the advantages of metal organic framework materials in the adsorption and separation of C4 hydrocarbons,the adsorption and separation mechanism of C4 hydrocarbons by metal organic framework materials is analyzed.Latest research progress on the adsorption and separation of C4 hydrocarbons by various metal organic framework materials is summarized,and the existing problems and development directions of study on metal organic framework materials in the adsorption separation of C4 hydrocarbon are discussed.