In order to deal with chloromethane-containing tail gas in fine chemicals production,a set of chloromethane absorption-reaction coupling process is designed,in which absorption-reaction coupling tower is the key equipment.The design of the tower is studied deeply.This study provides a reference for enterprises to reduce cost,achieve emission standards and clean production,and also provides a reference for the design of tail gas treatment tower for chemical raw materials with low boiling point and high vapor pressure.