以氯金酸（HAuCl₄）为前驱体，酪氨酸（Tyr）为还原剂和保护剂，通过"一步合成法"合成了具有较强荧光且离散性良好的金纳米簇（Tyr-AuNCs）。优化并确定了制备Tyr-AuNCs的最佳工艺条件：80℃下反应20 min，Tyr质量浓度为0.4 mg/mL，HAuCl₄浓度为2.0×10^-3 mol/L，pH=5的乙酸（CH₃COOH）缓冲溶液。通过研究Tyr-AuNCs与Fe³⁺的作用机理发现，Fe³⁺可导致Tyr-AuNCs荧光探针猝灭，Tyr-AuNCs的荧光强弱与Fe³⁺的浓度（1.0~50 μmol/L）呈良好的线性关系，据此构建了水样中Fe³⁺的定量检测方法，该方法检出限为2.0×10^-7 mol/L，可用于实际水样中Fe³⁺的分析检测。

Tyr-AuNCs,a kind of gold nanoclusters with strong fluorescence and excellent dispersivity,is synthesized by using one-step synthesis method,with chloroauric acid (HAuCl₄) as a precursor,and tyrosine (Tyr) as a reducing agent and protective agent.The preparation method of Tyr-AuNCs is optimized and the optimum conditions are determined as follows:20 min at 80℃,0.4 mg·mL^-1 for Tyr concentration,2.0×10^-3 mol·L^-1 for HAuCl₄ concentration and acetic acid buffer solution with a pH value of 5.The mechanism of action between Tyr-AuNCs and Fe³⁺ is studied and it is found that Fe³⁺ can cause the fluorescence probe of Tyr-AuNCs to quench,and the fluorescence intensity of Tyr-AuNCs shows a good linear relationship with the concentration of Fe³⁺(1.0-50 μmol·L^-1).Hence,a quantitative detection method for Fe³⁺ in water sample is built up,with a detection limit of 2.0×10^-7 mol·L^-1,which can be used for the analysis of Fe³⁺ in actual water samples.

吴晗(1994-),男,硕士研究生,研究方向为新型纳米材料,398366635@qq.com