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摘要
基于牛血清白蛋白（BSA）保护的金纳米簇为荧光探针，通过甲磺酸帕珠沙星（PZFX）对其荧光的淬灭实现对PZFX的高灵敏度以及高选择性检测，检测限达2.9×10-8 g/mL。并将此方法用于人尿液样品中PZFX检测，检测结果表明，该方法具有简单、高效、灵敏度高和实用性强等特点，具有较好的应用前景。
Abstract
Gold nanoclusters protected by bovine serum albumin is used as fluorescent probe,pazufloxacin mesylate (PZFX) is detected with high sensitivity and high selectivity through PZFX's quenching against fluorescent.The detection limit reaches 2.9×10-8 g·mL-1.This method is also used to detect urine samples.The results indicate that this method has good application prospect with characters of simple,efficient,high sensitivity and strong practicability.
关键词
基于牛血清白蛋白
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尿液样品
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甲磺酸帕珠沙星
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金纳米簇
Key words
bovine serum albumin
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urine samples
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pazufloxacin mesylate
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gold nanoclusters
Author summay
胥彦琪(1984-),男,硕士,讲师,研究方向为生物制药技术,airln@qq.com
蛋白质保护的金纳米簇为荧光探针检测甲磺酸帕珠沙星[J].
现代化工, 2017, 37(9): 203-205 DOI:10.16606/j.cnki.issn0253-4320.2017.09.048
