研究了在微通道反应器内盐酸、双氧水对芳环的亲电氯化。利用盐酸和双氧水的混合物作为氯源与甲苯反应来合成氯代甲苯,考察了反应温度、原料配比、停留时间等因素对甲苯收率的影响。在氧氯化反应温度为75℃、n(甲苯)∶n(双氧水)∶n(盐酸)为1∶7∶3、停留时间为3.5 min时,一氯代甲苯的收率达到71%。

As important raw materials for fine chemicals,organic chlorides are playing an increasingly important role in industrial production.However,the chlorination reaction involving many chlorine gases faces severe pressure from environmental protection and safety,and half of chlorine atoms in the chlorination reaction are converted into hydrogen chloride,and the atom economy of chlorine is poor.In response to these problems,the electrophilic chlorination of aromatic rings by hydrochloric acid and hydrogen peroxide is studied in a microchannel reactor.The mixture of hydrochloric acid and hydrogen peroxide is used as the chlorine source to react with toluene to synthesize chlorotoluene.The influence of reaction temperature,raw materials ratio,residence time and other factors on the yield of toluene are investigated.The yield of monochlorotoluene reaches 71% when the oxychlorination reaction temperature is at 75℃,the molar ratio of toluene,hydrogen peroxide and hydrochloric acid is 1∶7∶3,and the residence time is 3.5 min.

李国梅(1996-),女,硕士生,研究方向为精细化工品,2454300489@qq.com