介绍了2022年美国（总统）绿色化学挑战奖获奖项目的概要、创新与价值。其中绿色合成路线奖授予默克公司开发的一种更环保的方法来制造LAGEVRIO^TM；绿色反应条件奖授予安进公司开发的一种用于生产治疗某些非小细胞肺癌新药的改进工艺；小企业奖授予农业科技公司Provivi开发的一种用于控制玉米毁灭性害虫（秋粘虫蛾）的生物信息素产品ProviviFAW^®；学术奖授予康奈尔大学宋林教授开发的一种效率更高的用于制药行业的大而复杂分子的产业化工艺；环境特别奖授予加利福尼亚大学戴维斯分校开发的一种利用果糖生产塑料化学品以减少温室气体排放的技术。

The overview,innovation and benefits of the awards and winners of 2022 US Green Chemistry Challenge Awards are reviewed.Merck & Co.,Inc.wins Greener Synthetic Pathways Award for developing a greener way to make LAGEVRIO^TM(molnupiravir),an antiviral treatment for COVID-19.Greener Reaction Conditions Award is won by Amgen for an improved manufacturing process for LUMAKRAS^TM Sotorasib,a novel drug for the treatment of certain non-small cell lung cancers.Small Business Award is won by Provivi for creating ProviviFAW^®,a biological pheromone-based product that controls the fall armyworm,a destructive pest of corn.Academic Award is received by Professor Song Lin of Cornell University for developing a new,more efficient process to create large and complicated molecules that are widely used in the pharmaceutical industry.Professor Mark Mascal of the University of California wins Specific Environmental Benefit—Climate Change Award for a technology that reduces greenhouse gas emissions by producing chemicals for making plastics from biomass derived from sugar fructose rather than petroleum.