采用不同氧化条件对油/水溶性纳米磁进行聚多巴胺（PDA）功能化，合成了Fe₃O₄@PDA-NaIO₄和Fe₃O₄@PDA。通过对其进行一系列表征发现，Fe₃O₄@PDA-NaIO₄和Fe₃O₄@PDA均具有较好的分散性，在pH 7.0下带相反电荷（+29.9 mV和-26.3 mV）；两者饱和磁化强度分别为48.80 emu/g和62.11 emu/g，磁性能良好，且均具有超顺磁性。合成的PDA功能化纳米磁有望应用于核磁共振成像、靶向药物递送等生物医学领域。

Fe₃O₄@PDA-NaIO₄ and Fe₃O₄@PDA are synthesized through functionalizing oil/water soluble magnetic nanoparticles by polydopamine (PDA) under different oxidation conditions.Through a series of characterizations, it is found that both Fe₃O₄@PDA-NaIO₄ and Fe₃O₄@PDA exhibit good dispersion and carry opposite charges at pH=7.0(+29.9 mV and -26.3 mV), which is due to the different compositional structures of PDA on both surfaces.In addition, the saturation magnetization intensity of these two particles is 48.80 emu·g^-1 and 62.11 emu·g^-1, respectively, both showing superparamagnetic.In conclusion, the synthesized PDA-functionalized magnetic nanoparticles are expected to be applied in biomedical fields such as nuclear magnetic resonance imaging and targeted drug delivery.

孟小琪(1996-),女,硕士研究生,研究方向为功能化磁性材料及水凝胶,polymermxq@163.com。