瘦肉精类药物是食品安全领域的一大严峻问题，如何高效快速地检测这类药物成为有效监管的重要环节。归纳总结了近年来此类药物残留量的标准检测方法以及在此基础上研发出来的改进方法和新型检测技术，包括前处理方法和后续检测技术。前处理方法主要介绍了固相萃取、固相微萃取、基质固相分散萃取及分子印迹等技术；检测技术概括了色谱检测、免疫分析及多种新型技术。通过分析性能指标数据说明各类检测方法的优缺点，指出检测技术将逐渐向多种分析物同时检测、现场快速检测、痕量（或超痕量）污染物检测等方向发展。

Detection of clenbuterol drugs is a key problem in the field of food safety.How to detect such drugs efficiently and quickly has become an important link for the effective supervision in this field.This paper summarizes the standard detection methods, the improved methods and new detection techniques for residue amount of this kind of drugs in recent years, including pretreatment methods and subsequent detection techniques.Among pretreatment methods, solid phase extraction, solid phase microextraction, matrix solid phase dispersion extraction and molecular imprinting are reviewed.The detection technologies such as chromatographic spectrum detection, immunoassay and many new technologies are also introduced.The advantages and disadvantages of various detection methods are explained by analyzing the performance index data.It is pointed out that the detection technologies for clenbuterol drugs will develop gradually towards simultaneous detection of various analytes, rapid detection on the spot, detection of trace (or super trace) pollutants.

孙悦(1997-),女,硕士生,主要研究方向为环境分析化学,783908561@qq.com