通过调控溶液的pH、选择不同速率热退火方式，以四点星DNA分子瓦为建筑模块，根据沃森-克里克碱基互补配对原则和Hoogsteen氢键配对连接，选择性地组装成不同的DNA多面体结构。非变性聚丙烯酰胺凝胶电泳表征结果表明，在酸性条件（pH 5.5）及退火时间5.0 h下，分子瓦自组装成DNA变形四面体（tTET）结构；在中性条件（pH 8.0）及退火时间24.0 h下，自组装形成DNA八面体（OCT）结构。在中性条件（pH 8.0）下，只改变分子瓦黏性末端碱基的数目，直至形成不同数目的碱基对来产生不同强度的作用力，也能类似地组装成不同的DNA多面体结构。该结果也由非变性聚丙烯酰胺凝胶电泳进行了表征。

By regulating pH value of the solution and selecting different speeds of thermal annealing methods,four-point-star DNA molecular tiles are selectively assembled into different DNA polyhedral structures according to Watson-Crick base complementary pairing principle and Hoogsteen hydrogen bond pairing connection.Non-denaturing polyacrylamide gel electrophoresis (PAGE) shows that the tiles can be self-assembled into a DNA transmutative tetrahedron (tTET) under acidic condition (pH=5.5) for 5.0 h of annealing.DNA octahedra (OCT) can be formed under neutral condition (pH=8.0) for 24.0 h of annealing.Going further and changing only the number of sticky end bases of tiles under neutral condition (pH=8.0),they can form different numbers of base pairs with different strengths,which can be similarly assembled into different DNA polyhedral structures.This result is also characterized by non-denaturing PAGE.