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摘要
主要从超分子化学角度对虚拟共晶设计理论、超分子合成子设计理论以及基于COSMO-RS计算模型的共晶设计理论等进行了阐述,并对其在共晶设计与筛选中的应用进行了分析与讨论;同时对几种最新的共晶筛选方法进行了简要介绍,并对共晶设计的研究趋势进行了相关展望。
Abstract
From the perspective of supramolecular chemistry,this paper mainly elucidates the virtual eutectic design theory,the supramolecular synthesizer design theory and the eutectic design theory based on COSMO-RS calculation model.Applications of these theories in eutectic design and screening are also analyzed and discussed.Several latest developed eutectic screening methods are briefly introduced,and the research trend for eutectic design is predicted.
关键词
共晶
/
纯化
/
筛选
/
设计
Key words
eutectic
/
purification
/
screening
/
design
Author summay
药物共晶设计理论及筛选技术研究进展[J].
, 2020, 40(4): 46-50 DOI:10.16606/j.cnki.issn0253-4320.2020.04.011