Nb2O5/C-Si is prepared and its catalytic properties in conversion of biomass sugar to 5-hydroxymethylfurfural (HMF) are studied.The factors such as niobium oxide loading amount,reaction time,temperature and catalyst dosage are investigated.It is found the niobium oxide loading amount has important impact on the acidity amount and catalytic properties of the catalyst,and the selectivity of HMF.With the increase of niobium oxide loading amount,both the acidity amount of catalyst and the conversion rate of fructose increase while the selectivity of HMF increases firstly and decreases then.The highest yield of HMF can reach 82.8% over 5% Nb2O5/P-C-Si catalyst.