结合南京紫光精细化工厂生产实际，介绍了由100 t/a PMDA氧化反应器扩容至210 t/a的设计原理，在氧化反应温度为435~445℃、高温载体熔盐温度为380~390℃下，确定了反应器的设计尺寸为1 170根直径为Φ30×2.5 mm反应管，通过对氧化系统主要设备的核算，以产出PMDA的原料消耗为1.4、催化剂负荷为60 g/h、操作空速为4 000 h^-1的条件，实现现有设备的潜在能力发挥，达到了设计目的。

Combined with the actual production of Nanjing Ziguang Fine Chemical Factory,the design principle for expanding the capacity of a 100 t/a pyromellitic dianhydride (PMDA) oxidation reactor to 210 t/a is introduced.Under the conditions that the oxidation reaction temperature is 435-445℃ and the temperature of molten salt,a high temperature carrier,is 380-390℃,the design size of the oxidation reactor is determined as 1 170 reaction tubes with Φ30×2.5 mm of root diameter.Through calculating the main equipment of the oxidation system,the potential capacity of existing equipment is fully utilized under the conditions that the unit consumption of raw material per ton of PMDA is 1.4 tons,the load of isotoluene catalyst is 60 g·h^-1 and the operating space velocity is 4 000 h^-1.The purpose of the expansion design is achieved.