Study on reaction-separation coupling processes for cyclohexanone ammoximation
LIU Jian-wu1,2, WANG Wei-wei1, YAN Sheng-hu1,2, SHEN Jie-fa1,2, ZHANG Yue1,2
1. School of Pharmaceutical Engineering & Life Science, Changzhou University, Changzhou 213164, China; 2. Continuous Flow Engineering Laboratory of National Petroleum and Chemical Industry, Changzhou 213164, China
Abstract: A kind of reaction-separation coupling device is designed for cyclohexanone ammoximation.Separation of TS-1 and reaction liquid is settled through flocculation and sedimentation of TS-1 in this device.The effects of sedimentation time,reactants molar ratio,reaction temperature and residence time on reactant conversion,product selectivity and TS-1 sedimentation efficiency are investigated,and the process conditions are optimized.Ahe conversion of cyclohexanone reaches 96.7%,the selectivity of cyclohexanone oxime reaches 99.6%,and the TS-1 concentration in overflow liquid reduces 0.438 6‰ as n(H2O2):n(cyclohexanone)=1.0:1,n(NH3H2O):n(cyclohexanone)=1.8:1,reaction temperature maintains at 70℃,residence lasts for 70 min and sedimentation lasts for 6.5 min.
刘建武, 汪伟伟, 严生虎, 沈介发, 张跃. 环己酮氨肟化反应分离耦合工艺研究[J]. 现代化工, 2021, 41(3): 207-210.
LIU Jian-wu, WANG Wei-wei, YAN Sheng-hu, SHEN Jie-fa, ZHANG Yue. Study on reaction-separation coupling processes for cyclohexanone ammoximation. Modern Chemical Industry, 2021, 41(3): 207-210.