Abstract: This paper concerns improvements of the N,N-diethyl nerolamine synthesis process.The effects of reaction solvent,system temperature,material adding order,molar ratio of reactant batch feed and metal catalyst on the synthesis of nerolamine are investigated.The best process conditions determined through experiments are as follows:under a certain pressure,toluene is used as solvent,the molar ratio of isoprene to diethylamine is 1:25,alkali metal lithium is used as catalyst for reaction system,system temperature is set at 70℃,the reaction time is 21 h.After recovering the raw materials via atmospheric distillation,nerolamine is obtained by vacuum distillation and the reaction yield is 86.7% upon isoprene.
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