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现代化工  2019, Vol. 39 Issue (6): 159-161,163    DOI: 10.16606/j.cnki.issn0253-4320.2019.06.033
  科研与开发 本期目录 | 过刊浏览 | 高级检索 |
N,N-二乙基橙花基胺的合成工艺改进
赵倩, 吕新宇, 刘丽, 邱滔
常州大学石油化工学院, 江苏 常州 213164
Improvement of N,N-diethyl nerolamine synthesis process
ZHAO Qian, LV Xin-yu, LIU Li, QIU Tao
School of Petrochemical Engineering, Changzhou University, Changzhou 213164, China
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摘要 针对N,N-二乙基橙花基胺合成工艺进行改进,考察了反应溶剂、体系温度、投料顺序、反应物分批投料的摩尔比、金属催化剂等对合成橙花基胺的影响。确定出反应的最佳工艺条件为:以甲苯为溶剂,原料异戊二烯与二乙胺的摩尔比为1∶25,碱金属锂为反应体系催化剂,体系温度为70℃,反应时间为21 h。通过常压蒸馏回收原料后,减压蒸馏得到橙花胺,反应收率为86.7%(以异戊二烯计算)。
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赵倩
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邱滔
关键词:  N,N-二乙基橙花基胺  异戊二烯  二乙胺    
Abstract: This paper concerns improvements of the N,N-diethyl nerolamine synthesis process.The effects of reaction solvent,system temperature,material adding order,molar ratio of reactant batch feed and metal catalyst on the synthesis of nerolamine are investigated.The best process conditions determined through experiments are as follows:under a certain pressure,toluene is used as solvent,the molar ratio of isoprene to diethylamine is 1:25,alkali metal lithium is used as catalyst for reaction system,system temperature is set at 70℃,the reaction time is 21 h.After recovering the raw materials via atmospheric distillation,nerolamine is obtained by vacuum distillation and the reaction yield is 86.7% upon isoprene.
Key words:  N,N-diethyl nerolamine    isoprene    diethylamine
收稿日期:  2018-09-19      修回日期:  2019-04-08          
ZTFLH:  TJ55  
通讯作者:  邱滔(1967-),男,研究员,主要从事绿色化学工艺的研究,通讯联系人,0519-863300181,qiutao@cczu.edu.cn。    E-mail:  qiutao@cczu.edu.cn
作者简介:  赵倩(1993-),女,硕士研究生,研究方向为合成化学,332164799@qq.com
引用本文:    
赵倩, 吕新宇, 刘丽, 邱滔. N,N-二乙基橙花基胺的合成工艺改进[J]. 现代化工, 2019, 39(6): 159-161,163.
ZHAO Qian, LV Xin-yu, LIU Li, QIU Tao. Improvement of N,N-diethyl nerolamine synthesis process. Modern Chemical Industry, 2019, 39(6): 159-161,163.
链接本文:  
http://www.xdhg.com.cn/CN/10.16606/j.cnki.issn0253-4320.2019.06.033  或          http://www.xdhg.com.cn/CN/Y2019/V39/I6/159
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